Table 2 Parameter values and P values derived with the ET and DP models

 Ktrans

0.10 (0.09–0.12)

0.05 (0.04–0.05)

< 0.001

< 0.001^*

 Vp

1.02 (0.82–1.14)

0.58 (0.38–0.74)

< 0.001

< 0.001*

 Ve

8.12 (6.50–10.23)

7.86 (6.95–8.96)

0.39

0.39

 Kep

1.20 (0.94–1.44)

0.57 (0.51–0.68)

< 0.001

< 0.001*

 F

13.01 (12.26–14.79)

8.12 (6.86–8.74)

< 0.001

< 0.001*

 MTT

15.15 (12.12–17.33)

12.38 (11.03–14.19)

0.08

0.13

 Vp

3.03 (2.37–3.69)

1.46 (1.22–2.02)

< 0.001

< 0.001*

 Ve

6.17 (4.88–8.06)

6.31 (5.74–8.09)

0.61

0.61

 PS

8.32 (6.75–10.74)

4.01 (3.16–5.14)

< 0.001

< 0.001*

 E

43.63 (37.02–51.29)

38.72 (34.42–47.26)

0.52

0.63