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Table 3 Events during the follow-up

From: Long-term outcome of percutaneous radiofrequency ablation for periportal hepatocellular carcinoma: tumor recurrence or progression, survival and clinical significance

Classification of all events

Periportal HCC

(N = 56)

Nonperiportal HCC

(N = 177)

P value

Tumor Events after RFA

 LTP

*15 (28.8%)

24 (13.6%)

0.0099

 IDR

*23 (44.2%)

40 (22.6%)

0.0012

 Extrahepatic recurrence

*12 (23.1%)

14 (7.9%)

0.0010

 PVTT

16 (28.6%)

12 (6.8%)

<0.0001

2nd-line treatments

 TACE

1

3

–

 RFA

6

11

–

 TACE+RFA

11

18

–

 Surgical resection

3

4

–

 Liver transplantation

1

1

–

 Radiation therapy

1

0

–

 Systemic therapy

1

0

–

 Systemic therapy+TIPS

1

0

–

 Systemic therapy+TACE±RFA

5

9

–

 Support therapy

3

5

–

 Unknown

2

0

–

Major complication

0.1346

 Total

6 (10.7%)

9 (5.1%)

 Hepatic infraction

2

0

 Portal vein thrombosis

4

5

 Biloma

0

1

 

 Liver abscess

0

1

 

 Bleeding

0

2

  1. *Four patients in the periportal group were excluded to evaluate the LTP, IDR and extrahepatic metastasis due to technical failure of RFA