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Table 1 MR parameters for the IVIM-DWI and DCE-MRI sequences.

From: DCE-MRI is more sensitive than IVIM-DWI for assessing anti-angiogenic treatment-induced changes in colorectal liver metastases

MRI Parameters

Liver tumours (n=25 patients)

IVIM-DWI

DCE-MRI

Sequence

2D single shot echo planar imaging

3D gradient echo

Acquisition plane

Coronal

Coronal

Breathing mode

Free breathing

Breath holding

Total acquisition time [min:s]

10:25

04:18

Time per single acquisition [min:s]

02:05

04:18

Number of averages

5

1

Acquired voxel size [mm3]

3.1 × 3.1 × 5

3.1 × 3.1 × 5

Reconstructed voxel size [mm3]

1.56 × 1.56 × 5

1.56 × 1.56 × 5

Slice thickness [mm]

5

5

TR [ms]

5000

3

TE [ms]

60

0.89

Flip angle [˚]

-

11

Slices per slab

20

14

Slice gap [mm]

0

0

Slice oversampling [%]

-

14.3

Matrix (FE x PE)

128 × 128

128 × 128

FOV [mm2]

400 × 400

400 × 400

Dynamic measurements

-

40

Breath holding (pause 6 s after dyn2, dyn4,etc.)

no

yes

Receiver bandwidth [Hz/Pixel]

1860

650

Parallel acquisition (GRAPPA) (PE acceleration factor x reference lines)

2 × 30

2 × 24

Phase partial Fourier

7/8

no

Slice partial Fourier

-

6/8

Fat suppression

SPAIR

none

8 b-values [s/mm2]

0, 20, 40, 60, 120, 240, 480, 900

-

Diffusion times [ms]

δ = 14.6; Δ = 24

-

  1. TR=repetition time; TE=echo time
  2. FE=frequency encoding; PE=phase encoding; FOV=field of view
  3. GRAPPA=GeneRalized Autocalibrating Partial Parallel Acquisition
  4. SPAIR=SPectral Attenuated Inversion Recovery