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Table 1 MR parameters for the IVIM-DWI and DCE-MRI sequences.

From: DCE-MRI is more sensitive than IVIM-DWI for assessing anti-angiogenic treatment-induced changes in colorectal liver metastases

MRI Parameters Liver tumours (n=25 patients)
IVIM-DWI DCE-MRI
Sequence 2D single shot echo planar imaging 3D gradient echo
Acquisition plane Coronal Coronal
Breathing mode Free breathing Breath holding
Total acquisition time [min:s] 10:25 04:18
Time per single acquisition [min:s] 02:05 04:18
Number of averages 5 1
Acquired voxel size [mm3] 3.1 × 3.1 × 5 3.1 × 3.1 × 5
Reconstructed voxel size [mm3] 1.56 × 1.56 × 5 1.56 × 1.56 × 5
Slice thickness [mm] 5 5
TR [ms] 5000 3
TE [ms] 60 0.89
Flip angle [˚] - 11
Slices per slab 20 14
Slice gap [mm] 0 0
Slice oversampling [%] - 14.3
Matrix (FE x PE) 128 × 128 128 × 128
FOV [mm2] 400 × 400 400 × 400
Dynamic measurements - 40
Breath holding (pause 6 s after dyn2, dyn4,etc.) no yes
Receiver bandwidth [Hz/Pixel] 1860 650
Parallel acquisition (GRAPPA) (PE acceleration factor x reference lines) 2 × 30 2 × 24
Phase partial Fourier 7/8 no
Slice partial Fourier - 6/8
Fat suppression SPAIR none
8 b-values [s/mm2] 0, 20, 40, 60, 120, 240, 480, 900 -
Diffusion times [ms] δ = 14.6; Δ = 24 -
  1. TR=repetition time; TE=echo time
  2. FE=frequency encoding; PE=phase encoding; FOV=field of view
  3. GRAPPA=GeneRalized Autocalibrating Partial Parallel Acquisition
  4. SPAIR=SPectral Attenuated Inversion Recovery