Table 1 Comparison of clinical characteristics of patients with l-MTC and m-MTC
From: Ultrasound features of medullary thyroid cancer as predictors of biological behavior
Variable | N | l-MTC (n = 23) | m-MTC (n = 55) | P |
|---|---|---|---|---|
Age (years) | 47.0 ± 14.8 | 52.6 ± 10.0 | 0.114a | |
Preoperative Ct/tumor size (pg/mL/mm) | 31.43 | 42.87 | 0.042b | |
Gender | 0.010 | |||
Female | 40 | 17 (73.9) | 23 (41.8) | |
Male | 38 | 6 (26.1) | 32 (58.2) | |
Tumor size (cm) | 1.70 ± 1.52 | 1.75 ± 1.21 | 0.910 | |
≤ 1 | 30 | 12 (52.2) | 18 (32.7) | 0.107 |
>1 | 48 | 11 (47.8) | 37 (67.3) | |
Multifocality | 0.843 | |||
Yes | 25 | 7 (30.4) | 18 (32.7) | |
No | 53 | 16 (69.6) | 37 (67.3) | |
Extrathyroid extension | 0.892 | |||
Yes | 45 | 13 (56.5) | 32 (58.2) | |
No | 33 | 10 (43.5) | 23 (41.8) | |
Central lymph node metastasisc | 0.000 | |||
Yes | 35 | 2 (9.5) | 33 (60.0) | |
No | 41 | 19 (90.5) | 22 (40.0) | |
Lateral lymph node metastasisd | 0.004 | |||
Yes | 30 | 1 (20.0) | 29 (12.1) | |
No | 8 | 4 (80.0) | 4 (87.9) | |
Preoperative Ct level (pg/mL) | 0.035 | |||
≤ 100 | 19 | 10 (43.5) | 9 (16.4) | |
100–1000 | 31 | 6 (26.1) | 25 (45.4) | |
> 1000 | 28 | 7 (30.4) | 21 (38.2) | |
Biochemical curee | 0.002 | |||
Yes | 39 | 18 (90.0) | 21 (48.8) | |
No | 24 | 2 (10.0) | 22 (51.2) | |
T staging | 0.892 | |||
T1 + T2 | 33 | 10 (43.5) | 23 (41.8) | |
T3 + T4 | 45 | 13 (56.5) | 32 (58.2) | |
M staging | 1.000 | |||
M1 | 4 | 0 (0.0) | 4 (7.3) | |
M0 | 74 | 23 (100.0) | 51 (92.7) | |
N staging | 0.000 | |||
N0 | 35 | 20 (87.0) | 15 (27.3) | |
N1a | 13 | 2 (8.7) | 11 (20.0) | |
N1b | 30 | 1 (4.3) | 29 (52.7) |