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Table 3 The diagnostic performance of normalized iodine concentrations (NICs) of peritumoral and intratumoral regions and qualitative features for predicting MVI

From: Prediction of microvascular invasion of hepatocellular carcinoma: value of volumetric iodine quantification using preoperative dual-energy computed tomography

 

NIC*

Qualitative features

Outer layer 1

Outer layer 2

Inner layer 1

Inner layer 2

VOIO1

VOIO2

VOII1

Peritumoral enhancement

Non-smooth tumor margins

AUC

0.75

0.71

0.70

0.68

0.73

0.74

0.67

0.64

0.63

95% CI

0.58–0.91

0.53–0.89

0.52–0.87

0.50–0.85

0.57–0.90

0.58–0.91

0.49–0.85

0.45–0.83

0.44–0.82

  1. Abbreviations: AUC area under the ROC curve, CI confidence interval, VOI volume of interest
  2. * Data which was obtained in part of the patient group was excluded (VOII2, n = 33)