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Fig. 1 | Cancer Imaging

Fig. 1

From: CT features associated with EGFR mutations and ALK positivity in patients with multiple primary lung adenocarcinomas

Fig. 1

A 62 year-old female with two concurrent primary lung adenocarcinomas, one was located in the apical posterior segment of the left upper lobe (lesion A) (a), and the other was located in the right upper lobe (lesion B) (b). On CT, lesion A presented as a lobulated, solid nodule with spiculate and pleural traction. Lesion B exhibited light, poorly defined ground glass opacity (GGO). Haematoxylin-eosin (H & E) staining (c) showed that lesion A was an invasive lung adenocarcinoma with an acinar predominant subtype, and lesion B was a microinvasive lung adenocarcinoma with a lepidic predominant subtype. The ARMS method (e, f) revealed a 19_del mutation within exon 19 of the EGFR gene in both tumours

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Cancer Imaging

ISSN: 1470-7330

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