Table 2 proposed WB-MRI protocol for cancer screening in asymptomatic subjects of the general population

1

Whole-body (head to mid-thigh) T1W GRE, Dixon technique

Axial or coronal (5 mm slice thickness)

Mandatory

2

Whole-body (head to mid-thigh) T2W, TSE without fat- suppression

Axial or coronal (5 mm slice thickness)

Mandatory

3

Whole-body (head to mid-thigh) DWI, STIR fat suppression, contiguous slicing, multiple stations

• ADC calculations with mono-exponential data fitting

• 3D-MIP reconstructions of highest b-value images*

Axial (5 mm slice thickness)

2 b-values:

• b50–100 s/mm²

• b800–1000 s/mm²)

Mandatory

4

• Brain: T2W FLAIR

Brain: Axial (5 mm slice thickness)

Optional

5

• Lung: T1 GRE short echo-time single breath hold

Lung: Axial (< 3 mm slice thickness)

Optional

6

• Whole spine T1W, TSE

Sagittal (4–5 mm slice thickness)

Optional

7

• Whole spine STIR (preferred) or fat suppressed T2W

Sagittal (4–5 mm slice thickness)

Optional