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Table 2 proposed WB-MRI protocol for cancer screening in asymptomatic subjects of the general population

From: Whole-body magnetic resonance imaging (WB-MRI) for cancer screening in asymptomatic subjects of the general population: review and recommendations

 Sequence descriptionCharacteristicsRecommendation
1Whole-body (head to mid-thigh) T1W GRE, Dixon techniqueAxial or coronal (5 mm slice thickness)Mandatory
2Whole-body (head to mid-thigh) T2W, TSE without fat- suppressionAxial or coronal (5 mm slice thickness)Mandatory
3Whole-body (head to mid-thigh) DWI, STIR fat suppression, contiguous slicing, multiple stations
• ADC calculations with mono-exponential data fitting
• 3D-MIP reconstructions of highest b-value images*
Axial (5 mm slice thickness)
2 b-values:
• b50–100 s/mm2
• b800–1000 s/mm2)
Mandatory
Additional regional assessments:
4• Brain: T2W FLAIRBrain: Axial (5 mm slice thickness)Optional
5• Lung: T1 GRE short echo-time single breath holdLung: Axial (< 3 mm slice thickness)Optional
6• Whole spine T1W, TSESagittal (4–5 mm slice thickness)Optional
7• Whole spine STIR (preferred) or fat suppressed T2WSagittal (4–5 mm slice thickness)Optional
  1. W = weighted; TSE = turbo spin echo; STIR = short tau inversion recovery; GRE = gradient echo; DWI = diffusion weighted imaging; ADC = apparent diffusion coefficient; MIP = maximum intensity projection; FLAIR = FLuid Attenuated Inversion Recovery
  2. * Whole-body rotational 3D MIP images rotating along the cranio-caudal axis (≤3 degrees of rotation per frame), displayed using an inverted grey scale
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