Skip to main content

Table 1 overview of the 12 studies reporting WB-MRI in asymptomatic subjects of the general population

From: Whole-body magnetic resonance imaging (WB-MRI) for cancer screening in asymptomatic subjects of the general population: review and recommendations

  WB-MRI protocolPer-lesion analysisPer-subject analysisCancer detection
AuthorYearCountryMagnet strenghtT1W TSET1W GET2W FST2WDWIContrastCardiovascular sub-protocolClassification methodAll findingsNot relevant≥ RelevantHighly relevantn° of WB-MRI examinationsEntirely normal (no findings)Abnormal findings reportedWith relevant findings (requiring further evaluation)Suspected malignant cancersConfirmed malignant cancers
Goehde372005GER1.5 WB SSYcardiac,
WB-MRA
binary: 1 (non-relevant), 2 (relevant)32923370,8%9629,2% 298    8231.0%10,3%10.3%
Baumgart382007GER1.5 WB S Ycardiac,
WB-MRA
      1007      40,4%40.4%
Lo412008HKG3.0 WBSWB   binary: 1 (non-relevant), 2 (relevant)23421089,7%2410,3% 13286,1%12493,9%2418.2%43,0%43.0%
Takahara422008NED1.5 WB WBWB         10    110.0%110,0%110.0%
Hegenscheid432013GER1.5 WBWBSSoptionalcardiac,
WB-MRA
categorical system: 1(non-relevant), 2 (relevant benign), 3 (relevant unclear), 4 (relevant malignant)13,45512,40392,2%9907,4%620,5%2500    78731.5%622,5%  
Cieszanowski442014PLN1.5 WBWB    categorical system: 1 (non-relevant), 2 (moderately or potentially relevant), 3 (relevant)3375299788,8%37811,2%150,4%66671,1%65998,9%  71,1%71.1%
Tarnoki452015GER3.0WBWBWB WBYWB-MRAcategorical system: 1 (non-relevant), 2 (requiring further evaluation), 3 (relevant)684464,7%2435,3%11,5%2229,1%2090,9%1568.0%14,5%  
Ulus462016TUR1.5  WBWBSoptional       1163328,4%8371,6%1210.3%32,6%21.7%
Saya472017UK1.5 WBWB WB  categorical system: 1 (definitely benign), 2 (likely to be benign), 3 (equivocal), 4 (likely to be malignant), 5 (definitely malignant)      44    818.2%00,0%00%
Lee482018KOR1.5 WBWB    categorical system: 1 (benign), 2 (requiring further evaluation), 3 (malignant)50029058,0%21042,0%61,2%229167,0%21393,0%  62,6%20.9%
Perkins*392018USA3.0 WB WBWBNcardiac       209*    7033.5%41,9%4*1.9%
Hou402020USA3.0 WB WBWBNcardiac       1190        201.7%
Total 17,96116,33691,0%16259,0%840.5%621466 / 11655,7%1099 / 116594,3%999 / 333130,0%93 / 5233 1.8%41 / 3692 1.1%
  1. Abbreviations: T1W = T1 weighted; T2W = T2 weighted; TSE = turbo spin echo; GE = gradient echo; FS = fat saturated; DWI = diffusion weighted imaging; S = single anatomic segment; WB = whole-body; WB-MRA = whole-body magnetic resonance angiography
  2. * subjects included in this study are also included in the study by Hou et al. Therefore, they were not counted in the overall number of WB-MRI examinations, nor in the overall number of confirmed malignant cancers
\