Fig. 20
From: Nonprostatic diseases on PSMA PET imaging: a spectrum of benign and malignant findings
Signet-cell gastric adenocarcinoma with bone metastases in a 82-year-old patient with prostate cancer 5 years after radical prostatectomy and biochemical recurrence (PSA = 0.67 ng/mL). 68Ga-PSMA-PET/CT MIP (a), coronal and axial CT (b, d) and coronal and axial PET/CT (c, e) images show multiple osteoblastic lesions with intense uptake (arrows in C and E). The patient performed an endoscopy (f) due to dyspeptic symptoms and diagnosed a signet cell gastric carcinoma. Additionally, the discrepancy between low PSA level and high tumor burden on PSMA PET imaging, patient underwent a left femur percutaneous biopsy that histopathology confirmed metastatic adenocarcinoma from gastric origin (g)