Fig. 2
From: Tumor treating fields in the management of Glioblastoma: opportunities for advanced imaging
Illustrative treatment time course for a patient with GBM. After a pathologic diagnosis of GBM, patients who are fit for treatment typically undergo a course of combined radiation with concurrent TMZ for a period of three to six weeks. This is followed by a short treatment break of approximately one month followed by TTFields with concurrent TMZ for at least six months or until treatment failure. Breaks in the timeline highlight areas where imaging biomarkers could provide a predictive tool to aid the decision to pursue treatment (Point A), continue treatment via response assessment (Point B), and discontinue treatment due to progression (Point C)