Fig. 6
![Fig. 6](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs40644-019-0248-y/MediaObjects/40644_2019_248_Fig6_HTML.png)
Ex vivo evaluation of the microstructure changes after chemotherapy. a Adriamycin treatment significantly decreased the tumor cell density in the responders but did not in the nonresponders. The parameters were shown as the means ± SD (* P < 0.001, for comparison between control and treated tumors). b Representative H&E-stained tumor micrographs (original magnification, × 400) show tumor cell density which significantly decreased in the treatment responders as compared with the nonresponders. Scale bar, 50 μm