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Table 4 Diagnostic accuracy in differentiating between high-grade and low-grade endometrial stromal sarcomas based on selected MR imaging features

From: Utility of diffusion-weighted and contrast-enhanced magnetic resonance imaging in diagnosing and differentiating between high- and low-grade uterine endometrial stromal sarcoma

Parameters n TP TN FP FN Sensitivity Specificity Accuracy PPV NPV
Feather-like enhancement 20 10 9 0 1 90.9 (58.7–99.8) 100 (100–100) 95.0 (75.1–99.9) 100 (100–100) 90.0 (55.5–99.7)
 Reader 1 20 10 9 0 1 90.9 (58.7–99.8) 100 (100–100) 95.0 (75.1–99.9) 100 (100–100) 90.0 (55.5–99.7)
 Reader 2 20 10 9 0 1 90.9 (58.7–99.8) 100 (100–100) 95.0 (75.1–99.9) 100 (100–100) 90.0 (55.5–99.7)
Necrosis 20 10 6 3 1 90.9 (58.7–99.8) 66.7 (29.9–92.5) 80.0 (56.3–94.3) 76.9 (46.2–95.0) 85.7 (42.1–99.6)
 Reader 1 20 10 6 3 1 90.9 (58.7–99.8) 66.7 (29.9–92.5) * 80.0 (56.3–94.3) * 76.9 (46.2–95.0) 85.7 (42.1–99.6)
 Reader 2 20 10 6 3 1 90.9 (58.7–99.8) 66.7 (29.9–92.5) * 80.0 (56.3–94.3) * 76.9 (46.2–95.0) 85.7 (42.1–99.6)
Hemorrhage 20 10 5 4 1 90.9 (58.7–99.8) 55.6 (21.2–86.3) 75.0 (50.9–91.3) 71.4 (41.9–91.6) 83.3 (35.9–99.6)
 Reader 1 20 10 5 4 1 90.9 (58.7–99.8) 55.6 (21.2–86.3) * 75.0 (50.9–91.3) * 71.4 (41.9–91.6) 83.3 (35.9–99.6)
 Reader 2 20 9 5 4 2 81.8 (48.2–97.7) 55.6 (21.2–86.3) * 70.0 (45.7–88.1) * 69.2 (38.6–90.9) 71.4 (29.0–96.3)
  1. Data in parentheses are 95% confidence intervals
  2. TP True positive, TN True negative, FP False positive, FN False negative, PPV Positive predictive value, NPV Negative predictive value
  3. *, P < .05 McNemar test, as compared with the feather-like enhancement