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Table 4 Diagnostic accuracy in differentiating between high-grade and low-grade endometrial stromal sarcomas based on selected MR imaging features

From: Utility of diffusion-weighted and contrast-enhanced magnetic resonance imaging in diagnosing and differentiating between high- and low-grade uterine endometrial stromal sarcoma

Parameters

n

TP

TN

FP

FN

Sensitivity

Specificity

Accuracy

PPV

NPV

Feather-like enhancement

20

10

9

0

1

90.9 (58.7–99.8)

100 (100–100)

95.0 (75.1–99.9)

100 (100–100)

90.0 (55.5–99.7)

 Reader 1

20

10

9

0

1

90.9 (58.7–99.8)

100 (100–100)

95.0 (75.1–99.9)

100 (100–100)

90.0 (55.5–99.7)

 Reader 2

20

10

9

0

1

90.9 (58.7–99.8)

100 (100–100)

95.0 (75.1–99.9)

100 (100–100)

90.0 (55.5–99.7)

Necrosis

20

10

6

3

1

90.9 (58.7–99.8)

66.7 (29.9–92.5)

80.0 (56.3–94.3)

76.9 (46.2–95.0)

85.7 (42.1–99.6)

 Reader 1

20

10

6

3

1

90.9 (58.7–99.8)

66.7 (29.9–92.5) *

80.0 (56.3–94.3) *

76.9 (46.2–95.0)

85.7 (42.1–99.6)

 Reader 2

20

10

6

3

1

90.9 (58.7–99.8)

66.7 (29.9–92.5) *

80.0 (56.3–94.3) *

76.9 (46.2–95.0)

85.7 (42.1–99.6)

Hemorrhage

20

10

5

4

1

90.9 (58.7–99.8)

55.6 (21.2–86.3)

75.0 (50.9–91.3)

71.4 (41.9–91.6)

83.3 (35.9–99.6)

 Reader 1

20

10

5

4

1

90.9 (58.7–99.8)

55.6 (21.2–86.3) *

75.0 (50.9–91.3) *

71.4 (41.9–91.6)

83.3 (35.9–99.6)

 Reader 2

20

9

5

4

2

81.8 (48.2–97.7)

55.6 (21.2–86.3) *

70.0 (45.7–88.1) *

69.2 (38.6–90.9)

71.4 (29.0–96.3)

  1. Data in parentheses are 95% confidence intervals
  2. TP True positive, TN True negative, FP False positive, FN False negative, PPV Positive predictive value, NPV Negative predictive value
  3. *, P < .05 McNemar test, as compared with the feather-like enhancement