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Table 3 Diagnostic performance for detecting regional lymph node metastasis

From: Improved detection of metastatic lymph nodes in oesophageal squamous cell carcinoma by combined interpretation of fluorine-18-fluorodeoxyglucose positron-emission tomography/computed tomography

  Sensitivity (%) Specificity (%) PPV (%) NPV (%) Accuracy (%)
SUVmax > 2.6a 72.7 (65.4–79.1)b 76.1 (74.9–77.1) 32.4 (29.2–35.3) 94.6 (93.2–95.9) 75.6 (73.6–77.4)
Size > 10.2 mma 55.3 (47.7–62.7) 74.8 (73.6–76.0) 25.8 (22.2–29.2) 91.4 (89.9–92.8) 72.2 (70.1–74.2)
CT attenuation pattern (visual) 98.0 (94.0–99.5) 17.8 (17.2–18.0) 15.9 (15.2–16.1) 98.3 (94.7–99.5) 28.8 (27.7–29.2)
  1. CT computed tomography, NPV negative predictive value, PPV positive predictive value, SUVmax Maximum standardized uptake value
  2. aData were evaluated using cutoff value from ROC analysis
  3. bNumbers in parentheses are 95% confidence intervals
  4. Sensitivity: SUVmax vs. size, P = 0.001; SUVmax vs. CT attenuation pattern, P < 0.001; size vs. CT attenuation pattern, P < 0.001
  5. Specificity: SUVmax vs. size, P = 0.476; SUVmax vs. CT attenuation pattern, P < 0.001; size vs. CT attenuation pattern, P < 0.001
  6. Accuracy: SUVmax vs. size, P < 0.001; SUVmax vs. CT attenuation pattern, P < 0.001; size vs. CT attenuation pattern, P < 0.001