Table 2 Comparison of size, 68Ga-PSMA-HBED-CC uptake (SUVmax) and radiodensity (HUmean) between normal liver and liver metastases (all, PSMA-positive and PSMA-negative)
From: 68Ga-PSMA-PET/CT for the evaluation of liver metastases in patients with prostate cancer
Normal liver | All liver metastases | PSMA positive metastases | PSMA negative metastases | p-value | |
|---|---|---|---|---|---|
Number | 18 | 103 | 80 | 23 | |
Size in cm2 | 3.27 ± 4.73 (0.2–29.5) | 2.69 ± 4.95 (0.2–29.5) | 5.29 ± 3.23 (2.1–14.3) | ||
SUVmax 2D ROI | 4.84 ± 2.29 (2.9–10.7) | 8.37 ± 5.22 (1.0–26.3) | ≤0.05 | ||
9.84 ± 4.94 (3.6–26.3) | ≤0.001 | ||||
3.25 ± 1.81 (1.0–7.5) | ≤0.05 | ||||
SUVmax 3D ROI | 5.32 ± 2.28 (3.0–11.9) | 8.73 ± 5.53 (1.4–26.3) | ≤0.05 | ||
10.27 ± 5.28 (3.6–26.3) | ≤0.001 | ||||
3.40 ± 1.78 (1.4–7.8) | ≤0.001 | ||||
HUmean, CE-CT | 102.18 ± 17.09 (56.5–124.0) | 61.04 ± 25.10 (16.4–124.2) | ≤0.001 | ||
67.0 ± 21.49 (16.5–124.2) | ≤0.001 | ||||
30.35 ± 19.71 (16.4–65.0) | ≤0.001 | ||||
HUmean, unenhanced CT | 53.76 ± 8.89 (38.2–60.6) | 31.10 ± 13.94 (8.5–50.7) | ≤0.05 | ||
40.36 ± 11.05 (8.5–50.7) | ≤0.05 | ||||
19.07 ± 5.27 (13.1–26.5) | ≤0.05 |