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Table 2 Mean (standard differentiation) of the diffusion parameters obtained from DTI, and the bi- and tri-exponential models for each of the segmented tissue types

From: Mono, bi- and tri-exponential diffusion MRI modelling for renal solid masses and comparison with histopathological findings

 

DTI

Bi-exponential model

Tri-exponential model

MD [10− 3 mm2/s]

FA

fstar [%]

Dbi [10− 3 mm2/s]

ffast [%]

finterm [%]

Dtri [10− 3 mm2/s]

Healthy Cortex (n = 13)

2.16 (0.12)

0.38 (0.09)

10.1 (2.58)

1.93 (0.10)

4.14 (1.92)

28.8 (5.09)

1.41 (0.09)

Healthy Medulla (n = 13)

2.21 (0.14)

0.39 (0.08)

9.69 (2.90)

2.02 (0.11)

4.57 (1.74)

26.4 (6.65)

1.55 (0.12)

All solid lesions (n = 13)

1.94 (0.32)

0.47 (0.11)

11.6 (3.88)

1.71 (0.43)

7.30(3.29)

18.7 (5.02)

1.39 (0.35)

RCC (n = 11)

1.90 (0.32)

0.46 (0.10)

11.6 (3.45)

1.65 (0.40)

7.21 (2.88)

18.3 (5.35)

1.34 (0.33)

Cyst (n = 5)

3.04 (0.17)

0.37 (0.11)

1.88 (1.60)

2.90 (0.11)

1.18 (1.70)

8.31 (2.02)

2.74 (0.08)

Benign (n = 2)

2.18 (0.28)

0.48 (0.19)

11.6 (7.83)

2.04 (0.58)

7.76 (6.75)

20.9 (2.43)

1.68 (0.45)

Significancea

a, b, d, e, g, i

x, y, z

 

b, e, g, i

b, d, e, g, i

y, z

a, g, i

x, y

a, d, e, g,

x, y

b, e, g, i,

z

  1. a p-value smaller than 0.05 is considered significant
  2. RCC renal cell carcinoma, MD mean diffusivity, FA fractional anisotropy
  3. aa = healthy cortex vs. RCC, b = healthy cortex vs. cyst, c = healthy cortex vs. benign
  4. d = healthy medulla vs. RCC, e = healthy medulla vs. cyst, f = healthy medulla vs. benign
  5. g = RCC vs. cyst, h = RCC vs. benign, i = benign vs. cyst
  6. j = healthy cortex vs. healthy medulla
  7. x = healthy cortex vs. all lesions (Wilcoxon Signed Ranks Test), y = healthy medulla vs. all lesions (Wilcoxon Signed Ranks Test)
  8. z = healthy cortex vs. healthy medulla (Wilcoxon Signed Ranks Test)
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Cancer Imaging

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