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Table 3 Lesions at baselinea

From: 18F-FDG PET/CT response in a phase 1/2 trial of nab-paclitaxel plus gemcitabine for advanced pancreatic cancer

Lesion Location

nab-Paclitaxel 100 mg/m2

nab-Paclitaxel 125 mg/m2

All dose levels

 

(n = 13)

(n = 38)

(n = 51)

Baseline SUVmax

 

n (%)

n (%)

n (%)

Mean

(St Dev)

Median

Pancreas

11 (85)

32 (84)

43 (84)

6.9 (3.6)

6.4

Liver

8 (62)

29 (76)

37 (73)

7.6 (3.4)

6.6

Peritoneum

4 (31)

24 (63)

28 (55)

5.9 (3.9)

5.3

Mediastinal nodes

3 (23)

15 (39)

18 (35)

4.5 (2.9)

4.0

Lung

3 (23)

11 (29)

14 (27)

2.6 (3.0)

2.1

Pelvic nodes

2 (15)

7 (18)

9 (18)

6.8 (2.7)

7.6

Hilar nodes

2 (15)

7 (18)

9 (18)

3.8 (1.8)

4.1

Neck nodes

1 (8)

5 (13)

6 (12)

6.7 (4.8)

5.1

Omentum/mesentery

1 (8)

5 (13)

6 (12)

6.8 (2.2)

6.6

Pleura

4 (31)

2 (5)

6 (12)

2.8 (2.0)

1.8

Bone

1 (8)

2 (5)

3 (6)

5.0 (1.4)

4.2

Adrenal glands

0

3 (8)

3 (6)

2.7 (1.4)

2.1

Spleen

0

2 (5)

2 (4)

3.1 (0.3)

3.1

Skin

2 (15)

0

2 (4)

5.9 (1.8)

5.9

Muscle

0

2 (5)

2 (4)

5.3 (1.1)

5.3

Other

0

0

0

Not Applicable

 

Brain

0

0

0

Not Applicable

 

Kidneys

0

0

0

Not Applicable

  1. aBased on a nominal alpha of .05 (2-tailed) and using Fisher exact tests, the 2 groups differed significantly on number of lesions in only 1 site: the pleura (P = 0.031)