Table 1 Summary of symptoms, relevant clinical history and management for each patient in our series
From: CT findings in patients with Cabazitaxel induced pelvic pain and haematuria: a case series
Case number | 1 | 2 | 3 | 4 | 5 |
|---|---|---|---|---|---|
Symptoms | Lower pelvic and left flank pain | Lower abdominal and pelvic pain | Pelvic pain | Pelvic pain and dysuria | Pelvic pain |
Radiotheraphy | 64Gy in 32 fractions to whole pelvis in 2007 | 64Gy in 32 fractions to whole pelvis in 1996 | 70Gy in 35 fractions to whole pelvis in 2010 | 74Gy in 37 fractions to whole pelvis in 2006 | 20Gy in 5 fractions to right hemi-pelvis in 2015 |
Docetaxal theraphy | 7 doses starting March 2015 | 5 doses starting October 2014 | 7 doses starting August 2013 | 6 doses starting July 2015 | 8 doses starting April 2016 |
Cabzitaxel theraphy | 7Â doses starting October 2015 | 5Â doses starting May 2015 | 5 doses starting July 2014 | 7 doses starting March 2015 | 9 doses starting May 2016 |
Symptom management | Cessation of Cabazitaxel and short course of prednisolone | Cessation of cabazitaxel and short course of dexamethasone/prednisoloe | Cessation of cabazitaxel and short course of dexamethasone | Cessaiton of cabazitaxel without steroid theraphy | Cessaiton of cabazitaxel without steroid theraphy |
Cabazitaxel re-initiation | Successful without recurrent symptoms | Not attempted | Not attempted | Not attempted | Successful without recurrent symptoms |