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Table 5 Univariate analysis of the clinic characteristics associated to the positivity of mpMRI and 18F-CH PET/CT

From: Evaluation of tumor recurrences after radical prostatectomy using 18F-Choline PET/CT and 3T multiparametric MRI without endorectal coil: a single center experience

 

mpMRI

18F-CH PET/CT

OR (95% CI)

p value

OR (95% CI)

p value

Age, years

1.01 (0.93–1.10)

0.759

1.02 (0.93–1.12)

0.694

Preoperative PSA, ng/mL

1.05 (0.95–1.15)

0.344

0.98 (0.89–1.07)

0.630

Pathologic T stage, T3

4.24 (0.94–19.26)

0.061

2.86 (0.69–11.82)

0.146

Pathologic N stage, Nx

0.93 (0.26–3.41)

0.917

0.50 (0.13–1.86)

0.301

Pathologic Gleason score, > 7

4.62 (0.83–25.73)

0.081

13.91 (1.54–125.63)

0.019

Positive surgical margin

0.69 (0.19–2.53)

0.578

0.34 (0.09–1.30)

0.116

Perineural Invasion

1.30 (0.36–4.72)

0.691

1.02 (0.28–3.68)

0.973

PSA levels, ng/mL

 Post radical prostatectomy

20.66 (0.45–964.07

0.121

2.17 (0.71–6.63)

0.172

 On day of biochemical failure

30.90 (1.50–635.84)

0.026

2.48 (0.76–8.15)

0.135

 On day of MRI-PET/CT

1.62 (0.88–2.98)

0.122

1.64 (0.90–2.99)

0.110

 Lowest PSA level after surgery

16.77 (0.530–531.40)

0.110

2.03 (0.72–5.69)

0.180

Treatment before mpMRI/choline PET/CT

 Radical prostatectomy and hormonotherapy or radiotherapy

1.63 (0.38–6.87)

0.509

0.67 (0.16–2.73)

0.573

Time from prostatectomy

 To first PSA recurrence

0.99 (0.95–1.03)

0.568

0.98 (0.94–1.01)

0.217

 To MRI-PET/CT

1.00 (0.98–1.02)

0.807

0.99 (0.97–1.01)

0.203

PSA doubling time, months

1.02 (0.92–1.12)

0.772

0.94 (0.85–1.05)

0.271

  1. Statistically significant value, p < 0.05 are in bold