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Table 3 Diagnostic performance of computed tomography features for distinguishing follicular neoplasm from nodular hyperplasia

From: Comparison of computed tomography features between follicular neoplasm and nodular hyperplasia

CT features

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

A z value*

p value

Degree of attenuation

96.6

24.6

53.8

88.9

0.567

0.058

Pattern of attenuation

67.8

38.5

50

56.8

0.531

0.469

Configuration

64.4

63.1

61.3

66.1

0.620

0.009

Margin

0

90.8

0

50

0.519

0.679

Shape

83.1

40

55.7

72.2

0.68

0.001

Calcifications

18.6

90.8

64.7

55.1

0.546

0.142

Degree of enhancement

44.1

89.2

78.8

63.7

0.682

< 0.001

Pattern of enhancement

93.2

20

51.4

76.5

0.559

0.058

Presence of CT halo sign

71.2

83.1

79.2

76.1

0.771

< 0.001

  1. Note. — *, A z means the largest area under the receiver operating characteristic curve. CT computed tomography, PPV positive predictive value, NPV negative predictive value