From: Comparison of computed tomography features between follicular neoplasm and nodular hyperplasia
CT features | Nodular hyperplasia (n = 65) | Follicular neoplasm (n = 59) | p value |
---|---|---|---|
Degree of attenuation | |||
no visualization | 5 (7.7 %) | 0 (0 %) | <0.001 |
low | 44 (67.7 %) | 57 (96.6 %) | |
iso- | 15 (23.1 %) | 1 (1.7 %) | |
high | 1 (1.5 %) | 1 (1.7 %) | |
Pattern of attenuation | |||
homogeneous | 25 (38.4 %) | 19 (32.2 %) | 0.466 |
inhomogeneous | 40 (61.6 %) | 40 (67.8 %) | |
Configuration | |||
intraglandular | 41 (63.1 %) | 21 (35.6 %) | 0.003 |
expansile | 18 (27.7 %) | 34 (57.6 %) | |
exophytic | 6 (9.2 %) | 4 (6.8 %) | |
Margin | |||
smooth | 42 (64.7 %) | 34 (57.6 %) | 0.023 |
irregular | 1 (1.5 %) | 0 (0 %) | |
lobulated | 16 (24.6 %) | 25 (42.4 %) | |
poorly defined | 6 (9.2 %) | 0 (0 %) | |
Shape | |||
ovoid | 26 (40 %) | 10 (16.9 %) | 0.008 |
round | 29 (44.6 %) | 30 (50.9 %) | |
taller-than-wide | 10 (15.4 %) | 19 (32.2 %) | |
Calcifications | |||
none | 59 (90.8 %) | 48 (81.3 %) | 0.186 |
rim (eggshell) | 1 (1.5 %) | 2 (3.4 %) | |
nodular | 2 (3.1 %) | 6 (10.2 %) | |
punctate | 2 (3.1 %) | 0 (0 %) | |
mixed* | 1 (1.5 %) | 3 (5.1 %) | |
Degree of enhancement | |||
no/scant | 4 (6.2 %) | 0 (0 %) | < 0.001 |
decreased | 29 (44.5 %) | 18 (30.5 %) | |
iso- | 25 (38.5 %) | 15 (25.4 %) | |
increased | 7 (10.8 %) | 26 (44.1 %) | |
Pattern of enhancement | |||
homogeneous | 13 (20 %) | 4 (6.8 %) | 0.06 |
inhomogeneous | 52 (80 %) | 55 (93.2 %) | |
CT halo sign | |||
absent | 54 (83.1 %) | 17 (28.8 %) | < 0.001 |
present | 11 (16.9 %) | 42 (71.2 %) |