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Table 3 Correlations between early surrogate parameters and TTP

From: Volume-based growth tumor kinetics as a prognostic biomarker for patients with EGFR mutant lung adenocarcinoma undergoing EGFR tyrosine kinase inhibitor therapy: a case control study

Ā 

Correlation coefficient

P values

Ī”S1

āˆ’0.122

0.152

Ī”S2

āˆ’0.254

<0.001

Ī”V1

āˆ’0.226

0.154

Ī”V2

āˆ’0.277

<0.001

RR

āˆ’0.046

0.591

TTN

0.012

0.890

  1. Ī”S1, the percent change in tumor size based on uni-dimensional measurement at the first follow up; Ī”S2, the percent change in tumor size based on uni-dimensional measurement at the second follow up; Ī”V1, the percent change in tumor volume at the first follow up; Ī”V2, the percent change in tumor volume at the second follow up, TTN; time to nadir, TTP; time to progression, RR; response rate