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Table 3 Summary of the results of test accuracy in studies comparing whole-body MRI with FDG-PET/CT in the detection of sites of tumour recurrence within the liver

From: Evidence-based medicine and clinical fluorodeoxyglucose PET/MRI in oncology

Study

Population & setting

Reference standard

Outcome [95 % CI]

PET-CT

WB-MRI

Sensitivity

PPV

Sensitivity

PPV

Donati et al. (2010) [21]

Various (n = 37, Colorectal Cancer: n = 20)

Histology or follow-up

76 [64–86] %

93 [82–98] %

91 [80–96] %

100 [93–100] %

Schmidt et al. (2009) [16]

Recurrent Colorectal Cancer

Follow-up (mean 11 months)

86 [65–95] %

100 [82–100] %

100 [85–100] %

100 [85–100] %

Self-controlled study (n = 24)

Pfannenberg et al. (2007) [15]

Recurrent melanoma

Histology or 8 months follow-up

94 [81–98] %

100 [90–100] %

100 [90–100] %

100 [90–100] %

Self-controlled study (n = 64)

Laurent et al. (2010) [19]

Recurrent melanoma

Histology or 6 months follow-up

50 [15–85] %

100 [51–100] %

100 [51–100] %

100 [51–100] %

Self-controlled study (n = 35)

Jouvet et al. (2014) [20]

Recurrent melanoma

Histology or ≥6 months follow-up

100 [76–100] %

100 k[76–100] %

100 [76–100] %

92 [67–99] %

Self-controlled study (n = 37)

Weighted averages

(n = 90)

 

84 [77–90] %

97 [92–99] %

96 [91–98] %

99 [96–100] %