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Table 4 18F-FDG PET/CT in the detection of CRC recurrence in patients with different CEA patterns

From: Diagnostic value of 18F-FDG PET/CT as first choice in the detection of recurrent colorectal cancer due to rising CEA

 

PET/CT diagnostic properties

Sensitivity

Specificity

PPV

NPV

CEA quartiles

Q1 (n = 19)

100.0 %

92.9 %

83.3 %

100.0 %

Q2 (n = 18)

75.0 %

90.0 %

85.7 %

81.8 %

Q3 (n = 18)

70.0 %

100.0 %

100.0 %

72.7 %

Q4 (n = 18)

100.0 %

100.0 %

100.0 %

100.0 %

CEA rise type

1 increase (n = 30)

94.4 %

83.3 %

89.5 %

90.9 %

2 increases (n = 26)

70.0 %

100.0 %

100.0 %

84.2 %

>2 increases (n = 5)

100.0 %

100.0 %

100.0 %

100.0 %

Persistently elevated (n = 12)

75.0 %

100.0 %

100.0 %

88.9 %

  1. 18 F-FDG PET/CT 18F-fluorodeoxyglucose positron emission tomography/computed tomography, CRC colorectal cancer, CEA carcinoembryonic antigen, PPV positive predictive value, NPV negative predictive value