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Cancer Imaging

Open Access

Comparison of standard staging protocol and WB-MRI for initial staging of rectal cancer

Cancer Imaging201515(Suppl 1):S9

Published: 2 October 2015


Lung CancerRectal CancerStandard ProtocolPrimary Lung CancerAgreement Rate


To evaluate the clinical feasibility of whole-body magnetic resonance imaging (WB-MRI) including contrast-enhanced T1-weighted imaging (T1WI) and diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) in rectal cancer initial staging


This retrospective study was approved by our IRB and the requirement for informed consent was waived. A total of 133 patients (M:F=87:46, mean age 62.4 years) who underwent standard protocol (chest, abdomen computed tomography and rectal MRI), WB-MRI (WB-T1WI and DWIBS) at 3T for initial staging were included. One attending radiologist reviewed standard protocol and two attending radiologists reviewed WB-MRI in consensus. Finally, “true” M staging was obtained using either biopsy or follow-up imaging. Agreement of M-staging for rectal cancer was obtained between standard protocol and WB-MRI, between true M-stage and standard-protocol and WB-MRI.


The agreement for M-staging between standard protocol and WB-MRI was 83.5% (111/133). M- staging of WB-MRI agreed to that of standard protocol in 96.0% (97/101) for M0, and 43.7% (14/32) for M1. M-staging agreement between standard protocol and “true” M-staging was 86.5% (115/133): standard protocol agreed to “true” M-staging in 86.8% (99/114) for M0 and in 88.9% (16/18) for M1. WB-MRI showed 94.0% (125/133) of agreement to “true” M-staging: the agreement rates between the two were 97.4% (111/114) for M0 and 77.8% (14/18) for M1. One patient who was reported as having lung metastasis on both protocols was confirmed with primary lung cancer on biopsy.


WB-MRI showed high agreement with standard protocol for initial rectal cancer staging and “true” M-staging.

Authors’ Affiliations

Seoul National University Hospital, Seoul, South Korea
Kon-kuk University Hospital, Seoul, South Korea
National Cancer Center, Goyang, South Korea


© Yoon et al. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.