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Value of DWI- ADC and FUSION T2-DWI in the management of oncological patients

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Describe DWI MRI and fusion T2-DWI techniques and findings for detection and characterisation of tumours, list the current and potential applications of DWI in cancer patient management and review causes of false-positive and false-negative results in lesion detection.

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The detection and characterisation of malignant lesions can often be difficult, principally when the disease is small or when the tumour is combined with normal tissues.

Forty five patients with malignancies underwent both DWI MRI and T2-DWI to detect and characterise primary and metastatic tumours. We acquired DWI (b0, b400, b600), FAT SAT T1w imaging before and after gadolinium administration and STIR images. The standard reference was histopathology findings.


DWI-MRI and fusion T2-DWI imaging is a powerful clinical tool for directing the care of patients with cancer. Three- dimensional fusion imaging of high b value DW-MRI with anatomic imaging have a number of utilities including data presentations to clinicians for detecting and guiding biopsy to variable tumour.

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Correspondence to M Nazar.

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This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.

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Nazar, M., Saguier, F., Alarcon, L. et al. Value of DWI- ADC and FUSION T2-DWI in the management of oncological patients. Cancer Imaging 15 (Suppl 1), P52 (2015).

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