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Cancer Imaging

Open Access

Value of DWI volumetry for assessment of complete rectal cancer response after CRT

  • M Nazar1Email author,
  • A Vazquez1,
  • L Alarcon1,
  • M Pascuzzi1,
  • M Wirtz1 and
  • E Eyheremendy1
Cancer Imaging201515(Suppl 1):P47

Published: 2 October 2015


Rectal CancerResidual TumourDiagnostic PerformanceContent OrganisationLearn Objective

Learning objectives

To determine the diagnostic performance of DWI volumetry for the assessment of complete response after CRT in patients with locally advanced rectal cancer and to compare with volumetry on standard T2- weight MRI, by means of volumetric signal intensity measurements.

Content organisation

We retrospectively analyzed 25 patients with locally advanced rectal cancer. Patients underwent pre and post-CRT standard T2 weight MRI and DWI MRI. We placed free-hand regions of interest and each tumour-containing section to determine pre and post-CRT tumour volumes.

Histologic findings were the standard of reference.


Volumetry of the viable tumour remmants based on signal intensity characteristic on DW images after CRT was shown to be more valuable than volumetry of the tumour based on morphologic T2w images for the differentiation between a pCR and residual tumour in locally advanced rectal cancer.

Authors’ Affiliations

Hospital Aleman, Buenos Aires, Argentina


© Nazar et al. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.