Figure 16

58 year old female on trastuzumab (Herceptin). A. MUGA scan obtained after 3 months of therapy with Herceptin shows that the EF has dropped significantly to 49% (Figure16A). B. The ejection fraction recovers to 72% (Figure16B) 1 week after discontinuation of therapy. Trastuzumab is known to cause this effect, which is worsened with concomitant anthracycline administration.