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Table 3 Diagnostic accuracy of conventional imaging (CI) and PET/CT in detecting relapse of disease in all patients, according to the histological type, and for locoregional and systemic recurrence

From: The utility of 18 F-FDG PET/CT for suspected recurrent breast cancer: impact and prognostic stratification

  

Negative predictive value

Positive predictive value

Likelihood

 

n

 

95% CI

p

 

95% CI

p

Ratio*

All patients:

63

       

Conventional Imaging

 

7/13 (54%)

29–82

 

35/50 (70%)

59–84

 

1.3

PET/CT

 

19/22 (86%)

70–98

0.05

39/41 (95%)

84–99

0.003

9.8

Locoregional recurrence:

63

       

Conventional Imaging

 

41/53 (77%)

65–88

 

8/10 (80%)

44–96

 

8.6

PET/CT

 

42/42 (100%)

93–100

<0.001

20/21 (95%)

78–100

0.24

43

Systemic recurrence:

63

       

Conventional imaging

 

14/19 (74%)

50–89

 

31/44 (70%)

56–82

 

1.8

PET/CT

 

26/29 (90%)

74–97

0.24

33/34 (97%)

85–100

0.002

24.8

  1. CI = Confidence Interval; PET/CT = Positron Emission Tomography/Computerized Tomography. Significant p values in bold.
  2. *likelihood ratio = sensitivity/ (1-specificity).