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Table 3 Diagnostic performances of US features for malignant thyroid nodules

From: Ultrasound microflow patterns help in distinguishing malignant from benign thyroid nodules

US Features

Malignant Group (%)

Benign Group (%)

Sensitivity

Specificity

PPV

NPV

Accuracy

Solid composition

122 (97.6)

74 (60.2)

0.976

0.398

0.622

0.942

0.690

Hypoechogenicity or very hypoechogenicity

119 (95.2)

82 (66.7)

0.952

0.333

0.592

0.872

0.645

Irregular margin or extrathyroidal extension

44 (35.2)

7 (5.7)

0.352

0.943

0.863

0.589

0.645

Taller-than-wide shape

59 (47.2)

10 (8.1)

0.472

0.919

0.855

0.631

0.694

Microcalcification

84 (67.2)

9 (7.3)

0.672

0.927

0.903

0.735

0.798

Penetrating vessel ≥ 1

103 (82.4)

38 (30.9)

0.824

0.691

0.730

0.794

0.758

Crab claw-like pattern

80 (64.0)

13 (10.6)

0.640

0.894

0.860

0.710

0.766

Root hair-like pattern

10 (8.0)

3 (2.4)

0.080

0.976

0.769

0.511

0.524

  1. PPV positive predictive value, NPV negative predictive value