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Table 5 Univariable and multivariable Cox regression analysis for PFS

From: Portal hypertension in patients with hepatocellular carcinoma and immunotherapy: prognostic relevance of CT-morphologic estimates

Analysis

Univariate

Multivariate

Score factor

HR

95% CI

p value

HR

95% CI

p value

Age, years

 > 65

0.9

0.5 – 1.7

0.830

   

ECOG

 > 1

0.9

0.3 – 3.1

0.920

   

BCLC

C/D

1.9

0.6 – 6.2

0.310

   

Child–Pugh

B/C

1.2

0.6 – 2.4

0.650

   

AFP, ng/ml

 > 200

1.7

0.9 – 3.3

0.089

   

Sum of the TL, mm

 < 100

2.0

1.0 – 3.8

0.045

2.0

1.0 – 4.3

0.045

Albumin, g/l

Cont.,

0.9

0.9 – 1.0

0.015

1.0

0.9 – 1.1

0.809

Bilirubin, mg/dl

Cont

1.5

1.2 – 1.9

 < 0.001

1.5

1.0 – 1.9

0.048

INR

Cont

0.3

0.1 – 1.3

0.110

   

Creatinine, mg/dl

Cont

1.3

0.5 – 3.2

0.580

   

PH score

 ≥ 4

2.1

1.1 – 4.0

0.023

1.6

0.6 – 4.0

0.312

  1. Outcome events: n = 40
  2. ECOG Eastern Cooperative Oncology Group, BCLC Barcelona Clinic Liver Cancer, AFP alpha-fetoprotein, INR International Normalized Ratio