Table 3 Univariable and multivariable Cox regression analysis for OS

Age, years

 > 65

0.7

0.4 – 1.3

0.290

ECOG

 > 1

1.6

0.5 – 5.1

0.460

BCLC

C/D

0.8

0.3 – 2.0

0.570

Child–Pugh

B/C

1.7

0.8 – 3.5

0.170

AFP, ng/ml

 > 200

2.0

1.1 – 3.9

0.034

1.9

1.0 – 3.8

0.069

Sum of the TL, mm

 < 100

1.7

0.9 – 3.3

0.140

Albumin, g/l

Cont.,

0.8

0.7 – 0.9

 < 0.001

0.9

0.8 – 1.0

0.030

Bilirubin, mg/dl

Cont

1.9

1.5 – 2.5

 < 0.001

1.4

1.0 – 1.9

0.080

INR

Cont

0.6

0.2 – 1.9

0.400

Creatinine, mg/dl

Cont

1.0

0.4 – 2.5

0.970

PH score

 ≥ 4

5.8

2.7 – 12.0

 < 0.001

2.9

1.2 – 7.0

0.015