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Table 4 Multivariate analyses of variables that affected the survival of included patients(N=59)

From: Safety and efficacy of self-expandable metallic stent combined with 125I brachytherapy for the treatment of malignant obstructive jaundice

Variables

Univariate analysis

Multivariate analysis

Hazard ratio

95% CI

P value

Hazard ratio

95% CI

P value

Age

0.995

0.971-1.020

0.703

   

Gender

 Male

1

     

 Female

0.688

0.349-1.355

0.280

   

Location of obstruction

 Hilar bile duct

1

     

 Middle and distal bile duct

0.947

0.394-2.274

0.902

   

Etiology

 HCC

1

     

 Cholangiocarcinoma

0.621

0.283-1.365

0.236

   

 Metastatic cancer

0.759

0.343-1.680

0.497

   

Bismuth type

 II

1

     

 III

0.783

0.157-3.890

0.765

   

 IV

1.652

0.505-5.404

0.407

   

ECOG

 1

1

     

 2

0.839

0.408-1.725

0.634

   

Obstruction length

1.359

0.867-2.131

0.181

   

Stent number

 one

1

     

 two

0.763

0.336-1.734

0.518

   

Systemic anti-tumor therapy

 No

1

  

1

  

 Yes

0.493

0.218-1.116

0.090*

0.580

0.254-1.327

0.197

Treatment

 Stent alone

1

  

1

  

 Stent with brachytherapy

0.354

0.186-0.673

0.002*

0.383

1.365-5.005

0.004*

  1. HCC Hepatocellular carcinoma, ECOG Eastern Cooperative Oncology Group
  2. *p value ≤ 0.100 was considered to indicate statistical significance
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