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Table 3 Effect of different N stages on the risk of survival outcomes

From: Prognostic significance of cervical radiologic carotid artery invasion by lymph node on magnetic resonance imaging in nasopharyngeal carcinoma

N stage

AJCC system

Proposed system

OS

 

DFS

 

DFFS

 

OS

 

DFS

 

DFFS

 

HR (95% CI)

P

HR (95% CI)

P

HR (95% CI)

P

HR (95% CI)

P

HR (95% CI)

P

HR (95% CI)

P

N0

1 (reference)

 

1 (reference)

 

1 (reference)

 

1 (reference)

 

1 (reference)

 

1 (reference)

 

N1

2.50 (0.72–8.71)

0.150

1.66 (0.75–3.65)

0.208

1.52 (0.61–3.79)

0.370

2.62 (0.77–8.91)

0.123

1.38 (0.63–3.03)

0.419

1.30 (0.53–3.23)

0.569

N2

4.02 (1.18–13.69)

0.026

2.29 (1.05–4.98)

0.038

2.16 (0.88–5.33)

0.093

4.39 (1.26–15.34)

0.020

3.53 (1.62–7.71)

0.002

3.39 (1.38–8.31)

0.008

N3

7.72 (2.26–26.44)

0.001

4.97 (2.28–10.83)

 < 0.001

5.41 (2.22–13.16)

 < 0.001

9.48 (2.75–32.69)

 < 0.001

5.58 (2.52–12.38)

 < 0.001

5.88 (2.37–14.61)

 < 0.001

  1. Abbreviations: AJCC American Joint Committee on Cancer, OS overall survival, DFS disease-free survival, DFFS distant failure-free survival, HR hazard ratio, CI confidence interval
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