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Table 1 Clinical and pathologic information

From: CEUS LI-RADS for diagnosis of hepatocellular carcinoma in individuals without LI-RADS-defined hepatocellular carcinoma risk factors

Characteristic

RF+ group

(n = 315)

RF− group

(n = 388)

P

Mean age (y)a

52.4 ± 12.8 (22–75)

49.7 ± 12.0 (17–86)

0.061

Sex

 Men

265 (76.7)

306 (71.5)

0.076

Mean nodule size (mm)a

33.4 ± 21.6 (8–131)

36.5 ± 21.7 (7–196)

0.391

Liver backgrounds

 HBV infection

243 (77.1)

  

 Cirrhosis

218 (69.2)

  

 NAFLD- non cirrhosis

 

123 (31.7)

 

 HCV infection- non cirrhosis

 

198 (51.0)

 

 Other liver diseases- non cirrhosis

 

67 (17.3)

 

Liver nodules

(w = 328)

(w = 418)

 

Pathologic Analysis

 HCC

206 (62.8)

204 (48.8)

< 0.001

 DN/RN

6 (1.8)

7 (1.7)

0.873

 Focal nodular hyperplasia

13 (4.0)

28 (6.7)

0.104

 Hemangioma

15 (4.6)

25 (6.0)

0.397

 ICC

18 (5.5)

38 (9.1)

0.064

 HCC-ICC

4 (1.2)

2 (0.5)

0.261

 Biliary adenoma

3 (0.9)

4 (1.0)

0.953

 Neuroendocrine neoplasm

8 (2.4)

12 (2.9)

0.717

 Lymphoma

1 (0.3)

1 (0.2)

0.863

 Angiomyolipoma.

2 (0.6)

8 (1.9)

0.124

 Inflammatory pseudotumor

17 (5.2)

32 (7.7)

0.176

 Lipoma

2 (0.6)

7 (1.7)

0.201

No pathologic analysis

 Follow-up CT or MRI imaging - Hemangioma

34 (10.4)

50 (12.0)

0.494

  1. Note: Unless otherwise indicated, data are liver nodules(w = 328 or 418) or patients (n = 315 or 388) and data in parentheses are percentages. Mean data are ± standard deviation. HBV Hepatitis B Virus, HCV Hepatitis C Virus, NAFLD non-alcoholic fatty liver disease, NA not available, HCC hepatocellular carcinoma, DN dysplastic nodule, RN regenerative nodule, ICC inrrahepatic cholangiocarcinoma
  2. a Data in parentheses are range