Fig. 5

Example of a simulated “low-dose” or late acquisition at 4 h p.i. For comparison the 16 min/b.p. acquisition (right hand side) is shown alongside a sample re-binning of the same data for a guideline recommended 2 min/b.p. acquisition, with resultant reduction in image quality following a clinically standard application of 192 MBq of [⁶⁸Ga]Ga-PSMA-11. Owing to the short half-life of [⁶⁸Ga] (68 min) later acquisitions were limited by poor count statistics and noise. It should be noted that 2 min/bp in continuous bed motion (cbm) can take up to 16 min on previous generation SAFOV scanner designs