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Table 5 Comparison of therapeutic response evaluation between different PET criteria

From: Comparative analysis of different response criteria at early phase after PD-1 blockade in non-small lung cancer

Variables

PERCIST

iPERCIST

Controlled

Uncontrolled

Total

(κ)

Controlled

Uncontrolled

Total

(κ)

EORTC criteria

SULpeak

  Controlled

44

0

44

(κ = 0.71)

44

0

44

(κ = 0.41)

  Uncontrolled

4

6

10

7

3

10

  Total

48

6

54

51

3

54

MTV

  Controlled

25

1

26

(κ = 0.96)

26

1

27

(κ = 0.74)

  Uncontrolled

0

28

28

6

21

27

  Total

25

29

54

32

22

54

TLG

  Controlled

28

6

34

(κ = 0.73)

30

4

34

(κ = 0.63)

  Uncontrolled

1

19

20

5

15

20

  Total

29

25

54

35

19

54

  1. Abbreviations: CT Computed tomography, PET Positron emission tomography, RECIST Response Evaluation Criteria Solid in Tumors, irRECIST Immune modified Response Evaluation Criteria Solid in Tumors, PERCIST PET Evaluation Criteria in Solid Tumors, iPERCIST Immune modified Response Evaluation Criteria Solid in Tumors, EORTC European Organization for Research and Treatment of Cancer, SULpeak The peak standardized uptake value normalized by lean body mass, MTV Metabolic tumor volume, TLG Total lesion glycolysis, (κ) The value of agreement between two assessments using Cohen κ coefficient