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Table 3 Comparison of therapeutic response evaluation between different PET criteria

From: Comparative analysis of different response criteria at early phase after PD-1 blockade in non-small lung cancer

Variables

PERCIST

iPERCIST

Responder

Non-responder

Total

(κ)

Responder

Non-responder

Total

(κ)

EORTC criteria

SULpeak

  Responder

16

4

20

(κ = 0.71)

13

7

20

(κ = 0.62)

  Non-responder

3

31

34

2

32

34

  Total

19

35

54

15

39

54

MTV

  Responder

12

2

14

(κ = 0.89)

12

2

14

(κ = 0.89)

  Non-responder

0

40

40

0

40

40

  Total

12

42

54

12

42

54

TLG

  Responder

15

2

17

(κ = 0.91)

15

0

15

(κ = 0.91)

  Non-responder

0

47

47

2

37

39

  Total

15

49

54

17

37

54

  1. Abbreviations: CT Computed tomography, PET Positron emission tomography, RECIST Response Evaluation Criteria Solid in Tumors, irRECIST Immune modified Response Evaluation Criteria Solid in Tumors, PERCIST PET Evaluation Criteria in Solid Tumors, iPERCIST Immune modified Response Evaluation Criteria Solid in Tumors, EORTC European Organization for Research and Treatment of Cancer, SULpeak The peak standardized uptake value normalized by lean body mass, MTV Metabolic tumor volume, TLG Total lesion glycolysis, (κ) The value of agreement between two assessments using Cohen κ coefficient