Prospective evaluation of Gadoxetate-enhanced magnetic resonance imaging and computed tomography for hepatocellular carcinoma detection and transplant eligibility assessment with explant histopathology correlation

Table 5 Real-world sensitivity of LR-4/5 and viable LR-TR for HCC detection with CECT versus EOB-MRI

LR-4/5 (all HCC ≥ 5 mm at histopathology)
Size		CECT	EOB-MRI	p-value
Overall	R1	36.5 (38/104)	75 (78/104)	< 0.001
	R2	27.9 (29/104)	56.7 (59/104)	< 0.001
	pooled	32.2 (67/208)	65.9 (137/208)	< 0.001
Treated observations (all viable HCC at histopathology)
Size		CECT	EOB-MRI	p-value
Overall	R1	47.6 (20/42)	50 (21/42)	1.00
	R2	42.9 (18/42)	50 (21/42)	0.66
	pooled	45.2 (38/84)	50 (42/84)	0.64

Data are percentages, with numerators and denominators in parentheses
CECT contrast-enhanced computed tomography, EOB-MRI Gadoxetic acid-enhanced MRI, R1 reader 1, R2 reader 2

ISSN: 1470-7330