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Table 2 Histopathologic characteristics of liver lesions at explant pathology

From: Prospective evaluation of Gadoxetate-enhanced magnetic resonance imaging and computed tomography for hepatocellular carcinoma detection and transplant eligibility assessment with explant histopathology correlation

 

Non-treated lesions

HCC

cHCC-CCA

CCA

Benign

Total

Number of lesions (%)

104 (88.9)

2 (1.7)

1 (0.9)

10 (8.5)

117 (100)

Mean size ± SD (range, cm)

1.3 ± 0.63 (0.5–3.5)

1.5 (0.5–2.5)

1.0 (NA)

1.3 ± 0.8 (0.6–32)

1.3 ± 0.65 (0.5–3.5)

Number in subgroups (%)

 0.5–0.9 cm

34 (29.1)

1 (0.9)

–

4 (3.4)

39 (33.3)

 1–1.9 cm

56 (47.8)

–

1 (0.9)

4 (3.4)

61 (52.1)

 ≥ 2 cm

14 (12)

1 (0.9)

–

2 (1.7)

17 (14.6)

Differentiation (%)

 Well

9 (7.7)

–

–

–

9 (7.7)

 Moderately

92 (78.6)

1 (0.9)

1 (0.9)

–

94 (80.3)

 poorly

3 (2.6)

1 (0.9)

–

–

4 (3.4)

 

Treated observations

Viable HCC

Viable cHCC-CCA

Non-viable HCC

Total

Number of lesions (%)

42 (31.3)

2 (1.5)

90 (67.2)

134 (100)

Whole mean size ± SD (range, cm)

2.9 ± 2.0 (0.6–10.5)

3.0 (2.0–4.0)

2.4 ± 1.3 (0.2–6.0)

2.6 ± 1.6 (0.2–10.5)

Viable mean size ± SD (range, cm)

1.6 ± 1.3 (0.1–5.5)

1.1 (0.5–1.6)

0 ± 0

1.5 ± 1.2 (0.1–5.5)

Number in subgroups (%)

 <  2 cm

32 (23.9)

2 (1.5)

36 (26.8)

70 (52.2)

 ≥ 2 cm

10 (7.5)

–

54 (40.3)

64 (47.8)

Differentiation states (%)

 Well

4 (3)

–

–

4 (3)

 Moderately

36 (26.8)

–

–

36 (26.8)

 poorly

2 (1.5)

2 (1.5)

–

4 (3)

  1. HCC hepatocellular carcinoma, cHCC-CCA combined hepatocellular-cholangiocarcinoma, CCA cholangiocarcinoma, SD standard deviation