Nomogram based on spectral CT quantitative parameters and typical radiological features for distinguishing benign from malignant thyroid micro-nodules

Table 3 Diagnostic performance of the combined model with DSCT parameters and typical radiological features

Combined model	AUC (95CI%)	Sensitivity	Specificity	Cutoff value	P value
AP_40keV + Radiological	0.857 (0.818–0.897)	0.767	0.806	−0.196	< 0.001
AP_70keV + Radiological	0.823 (0.778–0.867)	0.750	0.771	−0.014	< 0.001
AP_100keV + Radiological	0.721 (0.668–0.775)	0.641	0.680	−0.217	< 0.001
APλHU+Radiological	0.858 (0.819–0.898)	0.791	0.800	−0.069	< 0.001
APNIC+Radiological	0.813 (0.768–0.858)	0.729	0.767	0.026	< 0.001
APNZeff+Radiological	0.759 (0.709–0.810)	0.692	0.718	0.005	< 0.001
VPNIC+Radiological	0.693 (0.637–0.749)	0.640	0.635	−0.320	< 0.001
VPNZeff+Radiological	0.691 (0.635–0.747)	0.651	0.618	−0.396	< 0.001

AP arterial phase, VP venous phase, λHU the slope of spectral HU curve, NIC normalized iodine concentration, NZeff normalized effective atomic number

ISSN: 1470-7330