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Table 1 Univariate analysis in the benign and malignant micro-nodule cohort

From: Nomogram based on spectral CT quantitative parameters and typical radiological features for distinguishing benign from malignant thyroid micro-nodules

Variable

Benign micro-nodule cohort (n = 170)

malignant micro-nodule cohort (n = 172)

F value /Zvalue /X2value

P value

AP

 40 keV(HU)

360.34 ± 53.26

282.83 ± 62.87

3.915

< 0.001

 70 keV(HU)

135.40 (123.98, 148.65)

114.60 (99.78, 127.45)

−8.514

< 0.001

 100 keV(HU)

81.50 (70.40, 92.80)

75.05 (64.50, 84.96)

−3.814

< 0.001

 λHU

4.67 ± 0.83

3.48 ± 0.93

1.780

< 0.001

 NIC

0.37 (0.32, 0.42)

0.30 (0.23, 0.34)

−8.974

< 0.001

 NZeff

0.82 (0.80, 0.85)

0.80 (0.77, 0.82)

−6.507

< 0.001

VP

 40 keV(HU)

281.95 (257.60, 317.55)

282.45 (246.02, 324.75)

−0.365

0.715

 70 keV(HU)

117.50 (105.63, 128.28)

115.35 (103.10, 130.78)

−0.103

0.918

 100 keV(HU)

74.06 ± 14.99

75.53 ± 13.04

1.867

0.334

 λHU

3.50 (3.06, 4.03)

3.46 (2.92, 4.04)

−0.502

0.616

 NIC

0.68 ± 0.11

0.72 ± 0.14

17.013

0.003

 NZeff

0.94 ± 0.02

0.95 ± 0.03

12.280

0.009

Radiological features

 Micro-calcification (presence)

46 (27.1%)

89 (51.7%)

21.806

< 0.001

 Enhanced blurring (presence)

62 (36.5%)

97 (56.4%)

13.644

< 0.001

  1. AP arterial phase, VP venous phase, HU CT value, λHU the slope of spectral HU curve, NIC normalized iodine concentration, NZeff normalized effective atomic number