Shear wave elastography for differentiating parathyroid neoplasms with malignant diagnosis or uncertain malignant potential from parathyroid adenomas: initial experience

Table 3 Areas under curve, best cut off points and diagnostic performance of quantitative and qualitative shear wave elastography features in differentiating between the parathyroid carcinoma/ atypical parathyroid tumor and parathyroid adenoma

SWE parameters^a	Parathyroid carcinoma /atypical parathyroid tumor (n = 16)	Parathyroid adenoma (n = 20)	AUC(95%CI)	Cut-off	Sen	Spe	PPV	NPV	p-value
Min SWV(m/s)	1.45	0.75	0.644(0.459–0.829)	1.15	0.69	0.60	0.58	0.71	0.113
Mean SWV(m/s)	2.4	1.9	0.813(0.669–0.956)	2.35	0.56	0.95	0.90	0.73	< 0.001
Max SWV(m/s)	3.1	2.6	0.795(0.645–0.946)	2.70	0.75	0.75	0.71	0.79	0.006
Min modulus (kPa)	6.1	1.7	0.620(0.428–0.813)	3.9	0.69	0.60	0.58	0.71	0.105
Mean modulus (kPa)	18.2	11.1	0.852(0.720–0.983)	17.05	0.63	1.0	1.0	0.77	< 0.001
Max modulus (kPa)	28.45	20.35	0.794(0.639–0.948)	21.90	0.81	0.75	0.72	0.83	0.009
Elastogram pattern									< 0.001
Negative	3 (18.8%)	18(90%)							< 0.001
Void center	1 (6.2%)	2(10%)							> 0.05
Stiff rim	5 (31.2%)	0							< 0.001
Colored lesion	7 (43.8%)	0							< 0.001

SWE Shear wave elastography; ^a: all the parameters were shown as the median values in the two group; SWV Shear wave velocity, modulus Young’s modulus, Sen Sensitivity, Spe Specificity, PPV Positive predictive value, NPV Negative predictive value

ISSN: 1470-7330