Table 2 Features of H3 K27M-altered gliomas
Common locations | Less common locations | Tumor margins & extent | Enhancement | ADC values | rCBV |
|---|---|---|---|---|---|
• Thalami (esp. adults) • Brainstem (esp. children) • Spinal cord | • Corpus callosum • Hypothalamus • Pineal gland • Tectum | • Usually well-defined and localized • Occasionally more widely infiltrative • Leptomeningeal dissemination common, esp. later in disease course | • Variable, but often less than expected for a high-grade tumor | • Variable, but generally low | • Variable, but generally increased |