Comparison of international guidelines for diagnosis of hepatocellular carcinoma and implications for transplant allocation in liver transplantation candidates with gadoxetic acid enhanced liver MRI versus contrast enhanced CT: a prospective study with liver explant histopathological correlation

Table 5 Comparison of variances in HCC sensitivity and specificity across guidelines with EOB-MRI and CECT using Levene’s test

LESION TYPE		SENSITIVITY			SPECIFICITY
LESION TYPE		σ _MR	σ _CT	p -Value	σ _MR	σ _CT	p -Value
> 1 cm All Path HCC	Reader #1	0.0140	0.053	0.037	0.044	0	< 10 ^–3
> 1 cm All Path HCC	Reader #2	0.099	0.010	0.011	0.088	0	0.010
> 1 cm imaging visible only	Reader #1	0.216	0.151	0.347	0.088	0	0.010
> 1 cm imaging visible only	Reader #2	0.148	0.033	0.015	0.207	0	0.010
All size All Path	Reader #1	0.183	0.066	0.019	0.044	0	< 10 ^–3
All size All Path	Reader #2	0.115	0.023	0.011	0.088	0	0.010
All size imaging visible only	Reader #1	0.258	0.167	0.179	0.088	0	0.010
All size imaging visible only	Reader #2	0.169	0.062	0.018	0.207	0	0.010

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