Fig. 4
From: Hybrid imaging with [68Ga]PSMA-11 PET-CT and PET-MRI in biochemically recurrent prostate cancer
A 66-year old patient referred for imaging due to biochemical failure of PCa after radical prostatectomy and ADT. The patient presented with a PSA level of 1.2 ng/ml. In MRI, a lesion in the prostate bed with hypointense to intermediate T2w signal, suspicious for PCa local recurrence is depicted (A, arrow). The lesion shows early contrast enhancement in the dynamic T1w (B, arrow) and distinct diffusion restriction with signal decrease in ADC map (C, arrow). However, in PET-CT (D) no pathological tracer uptake can be delineated. In PET-MRI, the cranial part of the local recurrence is masked by the physiological [68Ga]PSMA-11 accumulation in the urinary bladder (E), while its caudal part can be clearly delineated as a contrast enhancing lesion in the MRI part of the fused image (arrow, F), despite the lack in [68Ga]PSMA-11 uptake