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Table 1 Comparison of ultrasonic signs between the malignant nodules and benign nodules

From: Diagnostic performance of simplified TI-RADS for malignant thyroid nodules: comparison with 2017 ACR-TI-RADS and 2020 C-TI-RADS

Ultrasonic signs

Malignant nodules (n=519)

Benign

nodules (n=230)

OR

P value

Composition

 Cystic or almost completely cystic or spongiform

1

16

0.03

0.001f

 Mixed cystic and solid

11

70

0.05

 Solid or almost completely solid

507

144

25.23

Echogenicity

 Anechoic

1

23

0.02

0.001f

 Hyperechoic or isoechoic

18

90

0.06

 Hypoechoic

438

107

6.22

 Very hypoechoic

62

10

2.98

Shape

 Wider than tall

285

202

0.17

0.001b

 Taller than wide

234

28

5.92

Margin

 Smooth or III-defined

53

146

0.07

NA

 Lobulated or Irregular

409

84

6.46

 Extra-thyroidal extension

57

0

1.12

Echogenic Foci

 None or large comet-tail artifacts

213

185

0.17

0.001f

 Macrocalcifications

48

22

0.96

 Peripheral calcifications

3

1

1.33

 Punctate echogenic foci

255

22

9.13

  1. bChi square test
  2. fContinuity correction of chi square test