Skip to main content

Table 2 AEF of viable tumor before and after DEB-TACE

From: Arterial enhancement fraction in evaluating the therapeutic effect and survival for hepatocellular carcinoma patients treated with DEB-TACE

 

Whole patients (n = 158)

Patients excluding CR response (n = 144)

AEFpre (%)

p*

AEFpre (%)

AEFpost (%)

Decrease ratio

p

Whole patients

52.6 ± 14.2

52.5 ± 14.2

46.9 ± 16.5

0.12 (− 0.02, 0.26)

<  0.001

Child-Pugh class

 A

51.1 ± 13.9

0.012

51.1 ± 14.1

46.3 ± 15.8

0.09 (− 0.05, 0.26)

<  0.001

 B

57.9 ± 14.1

58.0 ± 13.4

49.2 ± 19.1

0.14 (0.04, 0.30)

0.002

AFP (ng/ml)

  ≤ 400

51.4 ± 14.9

0.279

51.4 ± 15.1

44.1 ± 16.9

0.14 (0.04, 0.26)

<  0.001

  > 400

54.2 ± 13.1

54.0 ± 13.1

50.3 ± 15.6

0.06 (− 0.12, 0.27)

0.019

Lesion margin

 Smooth

53.8 ± 12.9

0.219

53.9 ± 12.9

45.1 ± 16.5

0.17 (0.04, 0.29)

<  0.001

 Non-smooth

51.0 ± 15.6

51.0 ± 15.5

49.0 ± 16.5

0.06 (− 0.13, 0.22)

0.143

Macrovascular invasion invasion

 Absent

52.9 ± 14.3

0.758

52.8 ± 14.3

43.6 ± 16.8

0.17 (0.05, 0.29)

<  0.001

 Present

52.2 ± 14.1

52.2 ± 14.2

51.8 ± 14.9

0.05 (−0.20, 0.17)

0.516

Treatment response

 CR

53.3 ± 14.6

0.988

 PR

52.7 ± 13.3

52.7 ± 13.3

38.9 ± 13.8

0.26 (0.18, 0.37)

<  0.001

 SD

52.1 ± 15.0

52.1 ± 15.0

49.3 ± 16.1

0.05 (−0.03, 0.11)

0.029

 PD

53.0 ± 14.6

53.0 ± 14.6

55.5 ± 16.0

0.07 (−0.31, 0.17)

0.604

  1. Decrease ratio was expressed by median (interquartile range) because the distribution of it observed skewed
  2. AEF Arterial enhancement fraction, AFP α-fetoprotein, CR Complete response, PR Partial response, SD Stable disease, PD Progressive disease
  3. * p value for differences of AEFpre between subgroups
  4. p value for differences between AEFpre and AEFpost in patients without CR response