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Table 1 Summary of the biologic pathways and their respective molecular imaging probes included in this review

From: Novel applications of molecular imaging to guide breast cancer therapy

Biochemical/Metabolic Target Radiotracer/s
Glucose metabolism 18F-fluorodeoxyglucose (FDG)
Steroid Receptor Expression  
 Estrogen Receptor 18F-fluoroestradiol (FES)
 Progesterone Receptor 18F-fluoronorpregnenedione (FFNP)
 Androgen Receptor 18F-fluorodihydrotestosterone (FDHT)
HER2 Receptor Expression 89Z-trastuzumab, 64Cu-DOTA-trastuzumab,18F-fluorobenzamidoethylmaleimide (FBEM)
Cell proliferation: Thymidine analog 18F-fluorothymidine (FLT)
Amino Acid transport and metabolism 18F-flurocyclobutane-1-carboxylic acid (18F-fluciclovine)18F-fluoroglutamine (18F-Gln)
Poly (ADP-ribose) polymerase-1 (PARP-1) expression 18F-FluorThanatrace