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Fig. 3 | Cancer Imaging

Fig. 3

From: Novel applications of molecular imaging to guide breast cancer therapy

Fig. 3

18F-Gln-PET/CT (A imaged 67 min post injection) and FDG-PET/CT (B obtained 58 min post injection) images of a patient with ER-expressing breast cancer reveals radiotracer uptake in a left level III lymph node which at pathology demonstrated metastatic ER-positive invasive lobular carcinoma. 18F-Gln SUVMAX = 6.4 and FDG SUVMAX = 3.9. High uptake of 18F-Gln is reflective of large cellular glutamine pool size and low glutamine catabolism, expected for ER-positive tumors [151]. Modest FDG uptake is also consistent with the modest level of glucose metabolism that is typical for lower grader ER-positive tumors

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