Skip to main content

Table 2 Characteristics of the eligible articles

From: Prognostic value of cervical nodal necrosis on staging imaging of nasopharyngeal carcinoma in era of intensity-modulated radiotherapy: a systematic review and meta-analysis

First author

Year of Publication

City

Patient recruitment period

Total patients

Patients treated with chemotherapy

Patients with nodes

Patients with CNN

Imaging modality

Numbers of undifferentiated

+ non-keratinising types

AJCC /UICC Edition

Median follow-up time in months (range)

Patient group for analysis

CNN presence/absence in any nodal group

Li [19]

2013

Guangzhou

2003-2007

749

535

565

142

MRI

744

7th

60.7

(3-104)

N+ group

Zhang [20]

2017

Guangzhou

2009-2012

1302

1193

1302

448

MRI

1294

7th

47.8

(1.3-75.3)

N+ group

Zhou [21]

2018

Shanghai

2010-2011

354

300

320

143

MRI

353

7th

63

(Not mentioned)

All

Feng [22]

2019

Hangzhou

2007-2012

616

601

616

235

MRI

612

8th

62.6

(3.4 -119)

N+ group

Ai [23]

2019

Hong Kong

2005-2012

546

382

404

153

MRI

544

8th

82.3

(3.2-150)

N+ group

Xu [24]

2021

Xi’an

2006-2018

792

744

687

501

MRI

789

7th

46.2

(1.3-130)

All

CNN presence/absence in retropharyngeal nodes

Tang [25]

2014

Guangzhou

2003-2007

749

535

565

64/481 (RPN+)

MRI

744

7th

81

(3-127)

N+ group

CNN grades

Zhang [26]

2017

Guangzhou

2009-2012

1423

1310

1423

Grade 1: 213

Grade 2: 257

MRI

1415

7th

48.6

(1.3-76)

N+ group

CNN laterality

Xie [27]

2020

Guangzhou

2010-2013

733

634

559

No/unilateral CNN: 692

Bilateral CNN: 41

MRI

728

8th

62

(1.4-83.2)

All

  1. CNN Cervical nodal necrosis, AJCC/UICC American Joint of Cancer Committee/ Union for International Cancer Control, N+group Patients with metastatic nodes, RPN Retropharyngeal node, MRI Magnetic resonance imaging